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These ocular conditions not only cause discomfort and pain to the animals but can also impair their ability to locate feed and water, further exacerbating nutritional deficiencies and impacting their overall health and well-being

Invasive procedures, such as central venous catheterization and lumbar puncture, should be avoided during the induction phase because of the high hemorrhagic risk during the initial phase of APL treatment.6,7 Management of hyperleukocytosis (white blood cell count 10 103/L) APL patients usually present with pancytopenia

three studies classified children as PA using this measure, further confirmed by high DHEA(S) levels (, , ), and Shirtcliff et al