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The same authors found that the L-tyrosine analogue (S)--fluoromethyltyrosine (AFMT), a nontoxic selective inhibitor of TDC (but not AADC), inhibited gut microbial levodopa decarboxylation in vitro

The most common symptoms include an upset stomach or diarrhea

Clinical trials demonstrated its ability to reduce visceral adipose tissue (VAT) and improve trunk fat distribution in the HIV lipodystrophy population

However, these membrane permeabilizing agents are not nutrient metabolites, play no essential metabolic role, and in fact they typically impair membrane function

This increase in norepinephrine stimulates -adrenergic receptors in the brains satiety center, inducing a stress-response signal that diminishes hunger