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[] OCDs underlying pathophysiology is a complicated environmental, neurological, and hereditary interaction [Figure 1]

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Intracellular signals can activate mTORC1 mainly through Rag GTPases and Ras homolog enriched in brain (Rheb) GTPases at the surface of lysosomes stimulated by amino acids and growth factors, respectively 61

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360 Furthermore, early clinical evaluation of Azeliragon (20 mg/day) with radiotherapy indicates a favorable safety profile, with no dose-limiting toxicities or treatment-related discontinuations

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The activity of glutathione peroxidase can be expressed by the rate of enzymatic reaction

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