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However, excessive production or metabolic imbalance of these highly reactive and unstable free radicals can lead to oxidative stress (OS)

Furthermore, TGF- stimulates the differentiation of cultured myoblasts into a fibrogenic cell type [44]

doi: 10.1038/mt.2016.159 124 WangQRenYMuJEgilmezNKZhuangXDengZet al

The two human 3-hydroxysteroid dehydrogenases have been investigated in detail by Thomas and coworkers (e.g., Thomas et al., 2005), and their studies indicate that the 3-ketosteroid 5-AD formed by oxidation of dehydroepiandrosterone with NAD + as a coenzyme remains as an intermediate bound to the enzyme prior to its isomerization to 4-AD

Deze verbindingen worden aangeduid als gebufferde vormen van vitamine C