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Changes in human Prx2 expression or oxidation state have been associated with several diseases: alterations in Prx2 expression have been reported in different types of cancer [83, 84]

GH action is mediated by the binding of GH to the growth hormone receptor (GHR), resulting in its dimerization and the auto-phosphorylation of the tyrosine kinases, Janus kinase 2 (JAK2), which, in turn, stimulates phosphorylation of signaling proteins, STAT proteins STAT1, STAT3 and STAT5

Caution advised with a low protein diet and before surgery

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