foxo4 dri senolytic peptide human trial 2024 2025 Computational design of targeting FOXO4. a, Domains of FOXO4-DRI improves spermatogenesis in aged
FOXO4 DRI improves spermatogenesis in aged mice through reducing senescence associated secretory phenotype secretion from Leydig cells ScienceDirect Senolytics: from pharmacological inhibitors to immunotherapies, a promising future for patients' treatment npj Aging Molecular modelling of the FOXO4 TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells eBioMedicine Frontiers FOXO4 DRI regulates endothelial cell senescence via the P53 signaling pathway FOXO4 DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53 serine 15 phosphorylation Communications Biology
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