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Fat cell adrenergic receptors and the control of white and brown fat cell function

Wolffenbuttel BHR, Wouters H, de Jong WHA, Huls G, van der Klauw MM

While IGF-1 has important physiological functions, elevated levels carry potential concerns including increased cell proliferation that may support tumor growth in individuals with cancer or pre-cancerous conditions, accelerated aging processes through growth pathway activation, potential cardiovascular effects with chronic elevation, and metabolic consequences including effects on glucose and lipid metabolism

Peptides are extremely safe but in order to get the results you want there is often an order of operations to layering in peptides

Receptor binding kinetics matter