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Though promising, research into vitamins and supplements to treat ED is still in its infancy

167, 1997, pp

Animal studies have demonstrated that type 1 diabetes mellitus (T1DM) can lead to testicular atrophy, disruption of seminiferous tubule architecture, and impaired spermatogenesis through multiple mechanisms, including oxidative stress, apoptosis, endocrine dysregulation, autoimmune responses, and epigenetic alterations [4, 5]

*Correspondence: Richard Eugene Frye, Arkansas Childrens Hospital Research Institute, Slot 512-41B, 13 Childrens Way, Little Rock, AR 72202, USA e-mail: [email protected] This article was submitted to Child and Neurodevelopmental Psychiatry, a section of the journal Frontiers in Pediatrics

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