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In addition to antioxidant effects, scopoletin has potent anti-inflammatory activity

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For robust peer review, studies should combine at least two orthogonal redox readouts (e.g., ROS kinetics plus GSH/GSSG or lipid peroxidation), report time courses, and relate redox changes to mechanistic endpoints (e.g., death mode, pathway markers, or resistance phenotypes)

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Hospital-based IV therapy accounts for these differences through weight-based dosing, continuous monitoring, and pediatric-trained clinicians