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2 Major chemical components and pharmacological effects of Scrophulariae Radix 2.1 Major chemical components Scrophulariae Radix , a well-known TCM, contains various active constituents, including iridoids, phenylpropanoids, organic acids, volatile oils, steroids, carbohydrates, flavonoids, alkaloids, and phenols

Their anti-inflammatory action effectively limits the intensity and scope of the inflammatory response by directly inhibiting the release of inflammatory factors and related signaling pathways

RNA was quantitated using a high-sensitivity RNA tape (5067-5579

*Correspondence: Fabrizio Ginevri, [email protected] These authors have contributed equally to this work and share first authorship These authors have contributed equally to this work and share last authorship This article was submitted to Nephrology, a section of the journal Frontiers in Medicine Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Aasmets O, Lll K, Lang JM, Pan C, Kuusisto J, Fischer K, Laakso M, Lusis AJ, Org E