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Description

Importantly, Gclc overexpression boosts T cell anti-tumor functionality via glutathione synthesis and glutamate consumption

The SNPs glutamate-cysteine ligase catalytic subunit, GCLC , rs1555903

Darren Baroni, M.D

We found that PA increases the protein expression levels of the long-chain fatty acid transporter CD36, leading to increased lipid uptake

These interconnected processes collectively promote oxidative stress and neuronal injury, which is now recognized as a potential pathogenic mechanism in PD 92,93