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Non-human primates (NHPs), such as rhesus monkeys, naturally exhibit age related tau and amyloid (A) pathologies, providing models that closely mimic human disease progression (Li et al., 2019)

For patients who cannot tolerate topical applications during severe flares, oral peptide delivery circumvents the damaged skin entirely while still providing systemic anti-inflammatory effects

Additionally, the levels of protein expression of Nrf2 and NQO1 were reversed by two activators of Nrf2, bardoxolone (CDDO) and sulforaphane (SFN)

Song Y, Manson JE, Lee I-M, Cook NR, Paul L, Selhub J, et al

Do essential fatty acids play a role in brain and behavioral development