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10.1038/77535 87 VelzquezE.Le Baut AyusoY.BlzquezE.Ruiz-AlbusacJ

In general, JA is associated with resistance against necrotrophic microbes [43, 44]

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The glutathione disulfide (GSSG) formed can be recycled to GSH by glutathione reductase in the presence of NADPH

It seems that SARS-CoV-2 infection manipulates the necrosis process by regulating NF- B-dependent cell survival and mitochondria among various pathways to inhibit regulated necrosis and allow SARS-CoV-2 to replicate and spread