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The use of the glutathione in the present invention is necessary to reduce the oxidation stress that accompanies illnesses that decrease the methionine pathway function

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It downregulates ten-eleven-translocation protein 3 (TET3) and impairs the DNA demethylation at the paternal alleles of several insulin secretion genes such as glucokinase (GCK), thus making the offspring susceptible to impaired glucose tolerance and diabetes

doi:10.21873/anticanres.13721