acetaminophen overdose napqi glutathione mechanism authoritative source What is the antidote of choice for poisoning? N-acetylcysteine (NAC) Answer in the story ACETAMINOPHEN; FROM LIVER TO BRAIN:
ACETAMINOPHEN; FROM LIVER TO BRAIN: NEW INSIGHTS INTO DRUG PHARMACOLOGICAL ACTION AND TOXICITY PMC Acetaminophen metabolism. Acetaminophen is metabolized primarily by sulfation and glucuronidation. However, it can also be oxidized by CYPs to form NAPQI. NAPQI can then interact with cellular macromolecules, resulting in toxicity, or it can be detoxified NAPQI Alchetron, The Free Social Encyclopedia Acetaminophen Anesthesia Key Translational biomarkers of acetaminophen induced acute liver injury Archives of Toxicology Springer Nature Link
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