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A study evaluating the hepatotoxicity of columbin (CLB) demonstrated that CLB induces DNA damage both in vitro and in vivo, which is associated with the upregulation of PARP-1 (27)

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Improved Mitochondrial Function Underlies the Protective Effect of Pirfenidone against Tubulointerstitial Fibrosis in 5/6 Nephrectomized Rats

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8b), as the cholesterol is abundant in the cell membrane and may be co-purified with ABCC2