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Auld, D

Specifically, given the tolerability for substitutions outside of the binding interface, researchers could explore substitutions on the solvent exposed side of the peptide to recruit an E3 ligase to degrade Mdm2/X

10.1016/s0001-4079(19)32994-2 18 BeyE.PratM.DuhamelP.BenderitterM.BrachetM.TrompierF

At 24 h post-transfection, the cells were treated with AFB 1 for 24 h and then AFBO-GSH was extracted and quantified, which showed a significant increase in the production of AFBO-GSH in the AFB 1 -treated group (Fig