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A glutathione deficiency therefore leads to the activation of von Willebrand factor and the accumulation of ROS, which affect coagulation and platelet activation , impair endothelial function and predispose to the risk of thrombotic events , in particular hypercoagulation

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Moreover, previous studies have demonstrated that AP-associated multi-organ dysfunction (e.g., lung, kidney, liver) can be improved by TCM prescription treatment, such as Dachengqi decoction (Liu et al., 2023), Yinchenhao decoction (Zhao et al., 2024), and Chaiqin Chengqi decoction (Yang X