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Johnny Depp is celebrating his 57th birthday today but oh boy, does he even look a day older than 25

Worlds apart: The Green Lantern star ditched her typical polished glamour for the gritty role New role: The former Gossip Girl star is set to play a female spy in The Rhythm Section, a new espionage thriller produced by the team behind James Bond Exciting: Described as a 'female-driven international espionage thriller', The Rhythm Section will be an adaptation of British writer Mark Burnell's novel of the same name But after the distraught protagonist discovers the crash was no accident, Stephanie embarks on a mission to avenge her family's death

Symptoms include strong cravings, irritability, anxiety, depression, and difficulty concentrating when trying to quit, along with physical symptoms like increased appetite and weight gain

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LeibundGut-Landmann S, Weidner K, Hilbi H, Oxenius A