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Patch clamping was carried out using an EPC-10 amplifier and a PatchMaster software (HEKA, Lambrecht, Germany)

Immunosenescence contributes to: Increased infection risk Slower recovery from illness Reduced vaccine responsiveness Chronic inflammation Greater susceptibility to age-related diseases At the same time , many older adults experience "inflammaging," a state of persistent low-grade inflammation that accelerates biological aging

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