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Stern et al., 2022

P., Bernstein, M

But what if the problem isnt in your wrist

When capsaicin is applied topically, it binds to transient receptor potential vanilloid 1 (TRPV1) channels, causing a burning or stinging sensation, followed by a reduction in pain sensitivity due to the depletion of substance P, which is a neurotransmitter involved in the transmission of pain signals [96]