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Kalliomki M, Satokari R, Lhteenoja H, et al

Outline the -oxidation pathway by which fatty acids are metabolized to acetyl-CoA and explain how this leads to the production of large quantities of ATP from the reducing equivalents produced during -oxidation and further metabolism of the acetyl-CoA via the citric acid cycle

There are three scientifically plausible and complementary mechanisms that would deliver therapeutic benefit in MS, i.e., the anti-inflammatory properties of phytocannabinoids, inhibition of excessive glutamatergic neurotransmission/excitotoxicity mediated via CB 1 and CB 2 receptor activation, and direct action to facilitate neuronal firing mediated by CB 1 receptor activation [6669]

Usually, a food trial is performed before collecting biopsies unless there is a need for more urgent interventions, for example, if there is a high suspicion of cancer

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