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In biochemical and cellular research systems, DSIP has been examined for its involvement in neuroendocrine signalling, stress-associated pathways, and peptidereceptor interactions

"Anxiety" was the most central symptom at T1, while "depression" held the central position at subsequent time points

was supported by DBT Wellcome Trust India Alliance Team Science Grant (IA/TSG/19/1/600019)

Because c-Met/HGF signaling drives neurogenesis, dendritic branching, and synaptogenesis, and because Dihexa was reported to cross the blood-brain barrier, the compound attracted research interest as a candidate for enhancing synaptic connectivity in neurodegenerative disease and cognitive-impairment models