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Azide-Hexanoyl-Val-Cit-PAB(m-PEG8) fmoc Product Name DOTA-tris(t-Bu)ester-PEG4 Synonyms CAS

Azide-Hexanoyl-Val-Cit-PAB(m-PEG8) fmoc Product Name DOTA-tris(t-Bu)ester-PEG4 Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be finely tuned through selection

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Description

Product Name DOTA-tris(t-Bu)ester-PEG4 Synonyms CAS Number n/a Related CAS Molecular Formula C36H69N5O11 Molecular Weight 747

Product Name BG-DOTA Synonyms SNAP-DOTA CAS Number n/a Related CAS Molecular Formula C29H40N10O8 Molecular Weight 656

1038/s41589-020-0594-x

031 Purity (HPLC) >= 95% Solubility DMSO

2341796-80-1 (2HCl salt) Molecular Formula C31H49Cl2N5O4S Molecular Weight 658

Azide-Hexanoyl-Val-Cit-PAB(m-PEG8) fmoc Product Name DOTA-tris(t-Bu)ester-PEG4 Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be finely tuned through selection

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