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In diabetic wound, TNF superfamily, member 6 (FasL) expression induces keratinocyte apoptosis, leading to delayed healing (Liang et al., 2019

Cancer Lett 611

Moreover, they showed that sesamol prevented gut barrier damage by enhancing the expression of tight junction proteins (occludin, claudin-1, and ZO-1), recovering the loss of gut mucus layer while increasing SCFAs through changes in the gut microbiome structure by enhancing the relative abundance of Coprococcuscus, Butyricicoccus, Odoribacter, and AF12 [470]