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487 NQO1 inhibition may help overcome therapeutic resistance, as demonstrated in several preclinical and clinical trials

[DOI] [PMC free article] [PubMed] [Google Scholar] 53.Herr C., Greulich T., Koczulla R.A., Meyer S., Zakharkina T., Branscheidt M., Eschmann R., Bals R

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The study employed a randomized design, with patients receiving either rutin (500 mg) and ascorbic acid (500 mg) twice daily or a placebo for a duration of 6 weeks