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These results suggest that aged cells have alterations in the vesicular clearance mechanisms driven by Rab7 and Arl8b GTPases, which could be caused by the bioenergetic deficits of intracellular free GTP in old age

34,35 Thus, elevated exhaustion levels and reduced functional diversity of T cells may predict severe progression in patients with COVID-19

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Baseline Stroop time differences may add to OHE risk prediction over simple clinical models