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(left) UMAP of NT and perturbed cells, colored by perturbation condition

The science looked promising and the safety profile seemed reasonable

It is crucial for neurogenesis and has been implicated in mood regulation and cognitive function

E., Hussein, B., El-Seidi, E

2.4.1.1 Development of the detection algorithm While the Average PN algorithm had shown promise in previous clinical trials (Mrachacz-Kersting et al., 2016, 2019), it was not considered a BCI system (Mrachacz-Kersting et al., 2021), as it employed a predetermined timing in an open-loop manner to trigger stimulation during the neurofeedback sessions rather than real-time detection