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[Abstract]2023 Jan:310:136924

S.PetersS

The docking results showed that the ligand was bound to the hinge region of the kinase in a U-shape, the pyrazinone end was located inside the pocket, and the methylpiperazine ring was located outside the pocket, pointing to the solvent

In recent years, the prevalence of IBD has increased worldwide, with the highest incidence and pathogenicity observed in Northern Europe and North America (Ng et al., 2017)