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Methods Study design and participants This single-center, open-label, randomized controlled trial was conducted at Bhumibol Adulyadej Hospital

Most researchers report sustained benefits lasting 4 to 6 months post-cycle, which is why cycles are typically repeated only two to three times annually

(Amsterdam: Elsevier), 287312

UCP2 is a member of inner mitochondrial membrane proteins that dissipates the mitochondrial proton gradient by transporting H + across the inner membrane, thereby generating heat, stabilizing the inner mitochondrial membrane potential and reducing the formation of ROS (Pierelli et al

For overall weight loss, GLP-1 medications like semaglutide and tirzepatide have the strongest clinical evidence