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Two of the field-defining dihexa papers from the Journal of Pharmacology and Experimental Therapeutics were formally retracted in April 2025 for falsified and fabricated image data, with the retraction attributing the misconduct to Leen Kawas and James Harding (retraction record

Studies conducted by Khavinson's team and collaborating groups have suggested epithalon may modulate telomerase activity in human cell lines, with reactivation observed in some senescent fibroblasts and telomere extension measured by Southern blot or qPCR

These findings show that DUSP22 downregulation enhances Th1/Th17 differentiation, contributing to the progression of CHD

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In this process, a vital role in causing considerable harm to the Schwann cells and neurons in the peripheral nervous system is played by pro-inflammatory cytokines produced by cells that are resident or have infiltrated [26]