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YTHDF1 promotes breast cancer cell growth, DNA damage repair and chemoresistance

[6] Beyond a load dose of 1.1 mg, urinary excretion increased rapidly, so that with a dose of 2.5 mg, urinary output was 800 micrograms for a 24-hour urine collection

In the present study, we seek to investigate the protective effect of various endogenous metabolites of 17-estradiol (E 2 ) and estrone (E 1 ) against oxidative neurotoxicity using both in vitro and in vivo models, and also to determine the mechanism underlying their neuroprotective action