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There is a theoretical concern that very high doses may interfere with certain chemotherapy drugs that rely on oxidative mechanisms, so individuals undergoing cancer care should consult their oncologist before supplementing

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Cyanocobalamin, which must be processed by the body into the active form, is the most common type used in supplements

doi: 10.1158/0008-5472.CAN-06-0409

Tiny organelles inside cells that produce energy in the presence of oxygen