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Allergic reactions (e.g., ocular swelling, eyelid edema, and conjunctival hyperemia), corneal edema, iritis, ocular inflammation, ocular irritation, superficial keratitis, and superficial ocular infection have been reported in 1% to 10% of patients

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In addition, we found Hcy-induced neurodegeneration-like pathology changes of mitochondria via inhibiting the NAD + /Sirt1 pathway, including defects in mitochondrial morphology, mitochondrial biogenesis, and mitophagy, ultimately leading to impairments of synapse and cognition

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Some people may experience side effects from taking very high doses of vitamin B12 or receiving B12 injections above the vitamin B12 dosage recommendations