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doi: 10.1155/2017/8130796

Firstly, copper activates the autophagy process by upregulating the expression of autophagy-related genes such as Beclin1, ATG5, LC3, mTOR, and Dynein, 246,247 while also activating autophagic kinases ULK1 and ULK2

In patients with severe liver injury, hepatoprotective medications must be applied to prevent further damage in the liver

Three RCTs conducted in 2019 by Carlo Tenore et al

Despite these advantages, clinical translation remains limited by issues such as low solubility and potential cytotoxicity associated with certain inorganic materials [39, 40]