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Figure 2 It is worth noting that appropriate surface modifications can alter a drugs organ-targeting profile, enabling more precise delivery and allowing repurposing of existing materials, which helps reduce costs

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Since both SEACIT and TORC1 are localized to the vacuole membrane, information about dysfunctional mitochondria detected by vCLAMPs can be rapidly transferred to the adjacent TORC1 network to initiate degradation

References Barisic I, Balenovic D, Klicek R, Radic B, Nikitovic B, Drmic D, Udovicic M, Strinic D, Bardak D, Berkopic L, Djuzel V (2013) Mortal hyperkalemia disturbances in rats are NO-system related