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Am J Physiol Endocrinol Metab 292:E353E358

Phase 2 trial data (Jastreboff et al., NEJM 2023) demonstrated average weight reductions of approximately 1724% over 48 weeks notably higher than currently approved GLP-1 receptor agonists such as semaglutide, though direct comparisons are limited by differences in trial populations and designs

The deadline for written comments is July 22, 2026 the day before the meeting convenes

AOD 9604s journey in scientific exploration reveals intriguing findings: In preliminary studies, the peptide showcased an ability to induce weight loss without significantly impacting blood sugar levels, suggesting its potential as a targeted weight loss facilitator without metabolic disruptions [Ng et al., 2000]