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A method for stimulating a T cell-mediated immune response to a target cell population or tissue in a mammal, wherein said target cell population and/or tissue express ALPP and/or ALPPL2, or a region of ALPP and/or ALPPL2 bound by antibody M25AD, M25ADX and/or M25, said comprising: administering to a mammal an effective amount of a cell genetically modified to express a chimeric antigen receptor (CAR) according to any one of claims 88- 92

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Just as importantly, Ritual takes a less is more approach to formulation, focusing on nutrients that help fill common gaps rather than overloading its products with high doses or unnecessary ingredients