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60 The peroxiredoxins directly reduce H 2 O 2 and peroxynitrite, although this activity relies on a reduced thioredoxin system

Redox Rep 8, 2515 (2003)

Moreover, pharmacological inhibition of this cleavage delays neurodegeneration [386, 387]

Overall, while the majority of the RCTs demonstrated sound methodological practices, limitations in the reporting of blinding and randomization processes in a few studies should be taken into account when interpreting the overall findings of this scoping review