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It is known that SARS-CoV-2 induces pro-inflammatory cytokines up-regulation, leading to a cytokine storm (Barnes et al

Additionally, long-term safety of NTFs overexpression (e.g., aberrant plasticity, glial hyperplasia) and immunogenic risks of viral vectors require rigorous evaluation in preclinical and clinical settings

EC wrote the first draft of the manuscript and the cardiometabolic disorders section

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Precise regulation of differential distribution or expression of cytokines or signaling in intracellular and even subcellular structures may play a critical role in regulating FSP1-mediated programmed cell death