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The Journal of Physiology, 595 (3), 695-711

Despite spermidine-generated ROS being a possible upstream signal in activating the latter ATM pathway 206 , spermidine appears to act as direct ROS scavengers, resulting in inhibition of mitochondrial ROS production 211,212

Tsai PH, Liu JJ, Chiu WC, Pai MH, Yeh SL

Plenum Press, New York, pp 2537 Collinson LP, Dawes IW (1995) Isolation, characterization and overexpression of of the yeast gene, GLR1, encoding glutathione reductase