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Description

oral administration is degraded in the GI tract

Nerve Pain (Neuropathic Pain): Unlike nociceptive pain, neuropathic pain originates from the nerves themselves

143 PlattA.DavidB

At the tissue level, immunohistochemical staining for immature neurons, microglia and astrocytes were performed

Pharmacokinetic modeling and clinical experience support this approach, though no head-to-head randomized trial has compared 1.5 mg twice weekly versus 2.5 mg once weekly