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In vitro studies indicate that CYP2C8 primarily metabolizes pioglitazone, with a lesser role for CYP3A4 (Jaakkola et al., 2006)

A smaller proportion of participants taking bupropion were not smoking at 6 months vs

Normal tobacco has 4000 chemicals

Reynolds might add another brand that had to be sold off to Imperial Tobacco (along with the Kool, Salem, Winston and Maverick brands) to secure the approval of the Federal Trade Commission to purchase the Lorillard Tobacco Company