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(542) indicated that a diet high in polyphenols positively influenced gut permeability in ageing, leading to reduced serum zonulin levels

Ubiquitin-specific protease 4 is an endogenous negative regulator of metabolic dysfunctions in nonalcoholic fatty liver disease in mice

This dual mechanism explains why the compound produces such pronounced effects on adipose tissue lipid content without affecting lean tissue or overall energy intake in research models

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3.3.2 Enhancing cellular therapies through microbiotaBA axis modulation Although direct clinical evidence is limited, compelling mechanistic data suggest that modulating the gut microbiotaBA axis may augment cellular immunotherapies such as Chimeric Antigen Receptor T (CAR-T) cell therapy