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Description

Role of oxidative stress in refractory epilepsy: Evidence in patients and experimental models

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Finally, several reviews [147, 153] have synthesized this body of work, emphasizing how mitochondrial damage and mtDNA release create a vicious cycle: oxidative stress damages mtDNA, increasing its release, which then sustains inflammation and exacerbates amyloid and tau pathology

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C10-position imidazole-modified catalpol derivatives also showed significant inhibitory effects on the growth of human pancreatic cancer cells (PANC-1 and BxPC-3), with a 91.6% efficacy against BxPC-3 and 73.1% efficacy against PANC-1 (Kong et al., 2023b)

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Exosomes provide a protective and enriched source of miRNA for biomarker profiling compared to intracellular and cell-free blood PubMed Pentadecapeptide BPC 157 positively affects both non-steroidal anti-inflammatory agent-induced gastrointestinal lesions and adjuvant arthritis in rats ScienceDirect Chang, C

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These include selective serotonin reuptake inhibitors (SSRIs), serotonin and norepinephrine reuptake inhibitors (SNRIs), norepinephrine and specific 5-hydroxytryptamine antidepressants, as well as benzodiazepines (Zelek-Molik and Litwa, 2025)

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