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Furthermore, mathematical estimations based on the nicotine availability in VLNCs compared with NNC cigarettes with consideration of potential increases in bioavailability that could occur with intensive smoking suggest that substantial compensation would be impossible

(On the question of nicotine, while its an addictive chemical, its relative harms compared to cigarette smoking are minor outside of the context of pregnancy which is why public health officials have called for safer nicotine delivery systems.) Philip Morris is also highlighting its experience in Japan one of the countries where IQOS was first introduced as an example of the impact the product could have

Students were given study information and consent forms to read and share with their parents

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