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In many neurological diseases, comprising both neurodegenerative and neurodevelopmental disorders, alterations in DNA methylation occur at specific genomic regions, including gene promoters, enhancers and CpG islands (25)

mTOR complexes mTOR controls cellular metabolism by integrating signals from nutrients, growth factors, and other environmental cues

9 Impact of environmental factors on AA development Environmental factors, as in many other diseases, are considered significant contributors to both the onset and exacerbation of AA

Loss of pregnancy-associated plasma protein A extends lifespan in mice