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Chaperone-associated selective autophagy Chaperone-assisted selective autophagy (CASA) mediates lysosomal degradation of proteins delivered by a complex comprising HSC70, BAG3, and HSPB8

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Ex vivo analysis of mitochondria derived from rats subjected to ballistic injury revealed decreases in the enzymatic activity of pyruvate dehydrogenase and glutamate dehydrogenase, which reduce input from glucose and glucogenic AAs into the citric acid cycle (reduced CoA-SH and acetyl-CoA concentrations), at 24 h after injury [72, 75]

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