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260, 732739.10.1016/0003-9861(88)90503-6 110 TrakshelG

2, June 2018, pp

Kravats, A

It is naturally produced in the liver and plays a critical role in supporting the immune system, detoxifying the body, and protecting cells from oxidative stress and damage

The in vitro experiments have confirmed that vitamin D could inhibit the growth of Mtb and secretion of pro-inflammatory cytokines in peripheral blood monocytes (Martineau et al., 2007), stimulate the receptor-induced expression of antimicrobial peptides, and up-regulate LL37 gene to induce the autophagy-related proteins Atg5 and Beclin-1 to mediate the killing effect (Periyasamy et al., 2020)