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However, levels can fall with age, illness, chronic stress and environmental exposure

McFie, P

Results: Among 507 patients with AKI, 140 received RRT

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Hypoxia further complicates ROS-based therapies, but oxygen-independent strategiessuch as Fenton-like metal catalysts (Fe/Cu), hypoxia-activated prodrugs (HAPs), SDT, and NQO1 bioactivatable drugs (e.g., -Lapachone)show particular promise